AskDefine | Define serotype

User Contributed Dictionary

English

Noun

  1. serovar

Extensive Definition

For the term's use in bacteriology, see serovar.

Serotype (Allograft)

Transplants between genetically non-identical humans induce the creation of antibodies in the recipient. These non-identical cell-surface receptors between the donor and recipient produce antiserum reactive to the donor proteins. Under selection conditions one or two isoform specificities are obtained. This results in a serotype that is capable of identifying other individuals who have those proteins. This serotyping along with new-PCR based techniques are how tissues for organ-donor programs are characterized. (for more detailed information see Human leukocyte antigens and HLA Serotype tutorial.)
serotype in Spanish: Serotipo
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